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. Author manuscript; available in PMC: 2021 Oct 13.
Published in final edited form as: Mol Psychiatry. 2020 Oct 19;26(7):3108–3121. doi: 10.1038/s41380-020-00911-3

Table 2.

Time-lagged associations among pre-MVC PTSD, peritraumatic distress and dissociation, 2-week ASD, and 8-week PTSD based on univariate and multivariate regression models in the Freeze 1 AURORA MVC sample (n = 666)1.

Outcomes
Peritraumatic distress Peritraumatic dissociation Diagnoses of 2-week ASD2 Diagnoses of 8-week PTSD2
b (95% CI) b (95% CI) OR (95% CI) OR (95% CI)




I. Univariate associations 3
 Pre-MVC PTSD symptom score 0.3* (0.2-0.3) 0.3* (0.3-0.4) 1.9* (1.6-2.2) 1.9* (1.6-2.2)
 Peritraumatic distress score 2.1* (1.7-2.5) 2.0* (1.6-2.3)
 Peritraumatic dissociation score 2.1* (1.7-2.5) 1.7* (1.4-2.0)
 Continuous 2-week ASD symptom score 4.7* (3.7-5.9)
II. Multivariate associations with pre-MVC PTSD, distress and dissociation 4
 Pre-MVC PTSD symptom score 1.6* (1.3-1.9) 1.7* (1.4-2.0)
 Peritraumatic distress score 1.6* (1.3-1.9) 1.7* (1.4-2.1)
 Peritraumatic dissociation score 1.5* (1.2-1.8) 1.1 (0.9-1.4)
  χ22 57.6* 40.6*
  χ23 97.0* 84.9*
III. Multivariate associations with pre-MVC PTSD, distress and dissociation, and 2-week PTSD 4
 Pre-MVC PTSD symptom score 1.4* (1.1-1.7)
 Peritraumatic distress score 1.4* (1.1-1.8)
 Peritraumatic dissociation score 0.9 (0.7-1.1)
 Continuous 2-week ASD symptom score 4.1* (3.2-5.3)
  χ22 9.0*
  χ24 171.0*

Abbreviations. MVC, motor vehicle collision; PTSD, post-traumatic stress disorder; ASD, acute stress disorder; b, unstandardized linear regression coefficient; CI, confidence interval; OR, odds ratio.

*

Significant at the .05 level, two-sided test.

1

Based on a series of univariate and multivariate linear (when peritraumatic symptoms are the outcomes) and logistic (when diagnoses of 2-week ASD and 8-week PTSD are the outcomes) regression equations in which continuous measures of pre-MVC PTSD symptoms, peritraumatic distress, peritraumatic dissociation, and 2-week ASD symptoms are used to predict temporally subsequent variables in this series and 8-week diagnoses of PTSD. All predictor score are standardized to a mean 0 and variance of 1, allowing the ORs in models to predict diagnoses of 2-week ASD and 8-week PTSD to be interpreted as relative odds of these outcome diagnoses associated with a one standard deviation difference in predictor symptom scores. Preliminary analyses found that these linear transformations are appropriate and that nonlinearities and interactions among predictors are non-significant. In the cases of pre-MVC PTSD and 2-week ASD, these preliminary analyses found that the dichotomous variables defining diagnostic thresholds for pre-MVC PTSD and 2-week ASD were not significant in predicting later outcomes in models that included the linear continuous versions of the scales as additional predictors. See Supplementary Table 3 for these results.

2

Diagnoses of 2-week ASD and 8-week PTSD are dichotomies.

3

The results in this section of the table are based on models in which only one of the four row variables is used to predict one of the column variables.

4

The results in this section of the table are based on multivariate models in which all the row variables are used to predict one of the column variables.