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. 2021 Apr 5;12:615228. doi: 10.3389/fphar.2021.615228

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Copyright © 2021 Rehman, Ansari, Haile, Karim, Abujheisha, Ahamad and Imam.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of Thymus serrulatus essential oil (TS Oil) in carbachol (CCh)-induced contractions in the absence (control) and presence of different concentrations of (A) Thymus serrulatus essential oil (TS Oil) and (B) papaverine on the cyclic nucleotide content of guinea-pig trachea. Values shown are mean ± SEM of 3–4 individual experiments conducted on the isolated tracheal tissue preparations from 3 to 4 different guinea-pigs. *P < 0.05 and **P < 0.01, considered as statistically significant versus their respective controls (unpaired t-test).