TABLE 3.
Minimum Inhibitory Concentration (MIC) and Minimal Microbial Concentration (MMC) of Thymus serrulatus essential oil (TS Oil) vs. tested microbes and MIC of some antibiotics as per Clinical Laboratory Standard Institute (CLSI).
| Tested microbes | MIC | MMC | MIC (µg/ml) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Gentamicin | Cefuroxime | Cefepime | Ciprofloxacin | |||||||
| S | R | S | R | S | R | S | R | |||
| K. pneumoniae (NCTC 9633) | 95 μg/ml | 105 μg/ml | ≤4 | ≥16 | ≤8 | ≥32 | ≤2 | ≥16 | ≤1 | ≥4 |
| P. aeruginosa (ATCC 10145) | 105 μg/ml | 115 μg/ml | ≤4 | ≥16 | − | − | ≤8 | ≥32 | ≤1 | ≥4 |
| S. aureus (NCTC 6571) | 90 μg/ml | 100 μg/ml | Vancomycin | Gentamicin | Azithromycin | Tetracycline | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| S | R | S | R | S | R | S | R | |||
| ≤2 | ≥16 | ≤4 | ≥16 | ≤2 | ≥8 | ≤4 | ≥16 | |||
| *MRSA | 125 μg/ml | 137.5 μg/ml | − | |||||||
| *K. pneumoniae | 95 μg/ml | 125 μg/ml | ||||||||
| C. albicans (ATCC 14053) | 75 μg/ml | 100 μg/ml | ||||||||
*Clinical pathogens.
MIC, Minimum Inhibitory Concentration; MMC, Minimal microbicidal concentration; K. pneumoniae, Klebsiella pneumoniae; P. aeruginosa, Pseudomonas aeruginosa; S. aureus, Staphylococcus aureus; C. albicans, Candida albicans; MRSA, Methicillin-Resistant Staphylococcus aureus.