Figure 6.

In vivo HLV injection in Swiss mice using 0.5 μg of either naked p(3NF₁-Luc-3NF₂)c or naked p(Scr₁-Luc-Scr₂)c

(A) In vivo bioluminescence measured in treated legs (mean values ± SD of n = 5 limbs per group) until 7 days after injection is expressed in ph/pix/sec. The dashed line indicates the luminescence background. (B) Ex vivo luminescence measured in the homogenates of eight types of muscle. For each treatment, the value for each type of muscle is the average of n = 5 legs. Results are mean values ± SD given as RLU/mg of muscle. The background for each type of muscle was determined using a limb injected with 0.9% NaCl. ∗p ≤ 0.05 (Mann-Whitney test) between p(3NF₁-Luc-3NF₂)c and p(Scr₁-Luc-Scr₂)c.