Table 1.
Lipocalin-type Prostaglandin D Synthase (L-PGDS) Concentrations in the Lumbar and Perioptic Subarachnoid Space (SAS) with and without Serum Contamination in Normal-tension Glaucoma (NTG) Patients with Optic Nerve Sheath Compartmentation
| NTG Patients with Optic Nerve Sheath Compartmentation | |||||||
|---|---|---|---|---|---|---|---|
| Patient n | Age male | Age female | IOP (mmHg) | VF (dB) | L-PGDS Lumbar SAS (mg/L) | L-PGDS Perioptic SAS (with Contamination) (mg/L) | L-PGDS Perioptic SAS (without Contamination) (mg/L) |
| 1 | 81 | 12 | 15 | 28 | 45 | 127 | |
| 2 | 66 | 17 | 27 | 23 | 96 (OD)/102 (OS) | 120 (OD)/136 (OS) | |
| 3 | 70 | 16 | 20 | 30 | 26 | 33 | |
| 4 | 64 | 14 | 18 | 26 | 11 | 21 | |
| 5 | 82 | 12 | 23 | 4 | 38 | 71 | |
| 6 | 73 | 18 | 15 | 18 | 26 | 30 | |
| 7 | 67 | 13 | 25 | 25 | 29 | 45 | |
| 8 | 64 | 15 | 19 | 34 | 31 | 42 | |
| 9 | 83 | 15 | 24 | 18 | 33 | 52 | |
| 10 | 80 | 12 | 25 | 24 | 29 | 44 | |
| 11 | 72 | 13 | 26 | 29 | 61 (OD)/62 (OS) | 68 (OD)/69 (OS) | |
| 12 | 64 | 10 | 18 | 12 | 33 (OD)/24 (OS) | 41 (OD)/32 (OS) | |
| 13 | 62 | 17 | 26 | 21 | 104 | 144 | |
| AM ±SD | 72±7 | 66±9 | 14±2 | 23±4 | 24±8 | 33±27 | 45±39 |
Notes: L-PGDS was measured in the lumbar SAS at the level L3/L4 and in the perioptic SAS in the retrobulbar portion of the optic nerve. Intraocular pressure (mmHg) was measured by applanation tonometry. Visual field mean deviation was measured in decibels using standard automated perimetry. Age for male and female in years.
Abbreviations: IOP, intraocular pressure; VF, visual field; dB, decibels; OD, oculus dexter (right optic nerve); OS, oculus sinister (left optic nerve); AM, arithmetic mean.