Table 4.
Variable | Univariate hazard ratio | Multivariate hazard ratio | ||||||
---|---|---|---|---|---|---|---|---|
|
|
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Crude univariate HR | IPTW-adjusted univariate HR | Crude univariate HR | IPTW-adjusted multivariate HR | |||||
|
|
|
|
|||||
HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | |
Index surgery | ||||||||
| ||||||||
OS | - | - | - | - | ||||
| ||||||||
RS | 0.182 (0.081–0.410) | < 0.001 | 0.288 (0.146–0.566) | < 0.001 | 0.268 (0.118–0.605) | 0.002 | 0.302 (0.154–0.595) | 0.001 |
| ||||||||
LS | 0.440 (0.355–0.545) | < 0.001 | 0.553 (0.445–0.687) | < 0.001 | 0.535 (0.430–0.665) | < 0.001 | 0.534 (0.429–0.664) | < 0.001 |
| ||||||||
Age group (yr) | ||||||||
| ||||||||
≤ 54 | - | - | - | - | ||||
| ||||||||
≥ 55 | 3.327 (2.584–4.283) | < 0.001 | 3.065 (2.387–3.936) | < 0.001 | 2.751 (2.131–3.552) | < 0.001 | 2.598 (2.016–3.347) | < 0.001 |
| ||||||||
Health insurance | ||||||||
| ||||||||
Health insurance | - | - | ||||||
| ||||||||
Medical aid | 1.531 (0.860–2.723) | 0.148 | 1.492 (0.823–2.704) | 0.187 | ||||
| ||||||||
Income level | ||||||||
| ||||||||
High (> 25th percentile) | - | - | ||||||
| ||||||||
Low (≤ 25th percentile) | 0.991 (0.786–1.251) | 0.942 | 0.980 (0.775–1.240) | 0.867 | ||||
| ||||||||
mCCI score | ||||||||
| ||||||||
0–1 | - | - | - | - | ||||
| ||||||||
≥ 2 | 1.578 (1.277–1.951) | < 0.001 | 1.580 (1.276–1.957) | < 0.001 | 1.421 (1.149–1.757) | 0.001 | 1.460 (1.178–1.809) | 0.001 |
| ||||||||
Hysterectomy year | ||||||||
| ||||||||
2012–2014 | - | - | ||||||
| ||||||||
2015–2016 | 1.053 (0.819–1.354) | 0.689 | 1.071 (0.831–1.380) | 0.598 | ||||
| ||||||||
Risk group (adjuvant therapy) | ||||||||
| ||||||||
Low risk | - | - | - | - | ||||
| ||||||||
High risk | 3.574 (2.890–4.421) | < 0.001 | 3.267 (2.634–4.052) | < 0.001 | 2.658 (2.136–3.309) | < 0.001 | 2.762 (2.221–3.434) | < 0.001 |
| ||||||||
Geographical location | ||||||||
| ||||||||
Metropolitan | - | - | ||||||
| ||||||||
Other | 1.079 (0.864–1.347) | 0.502 | 1.015 (0.809–1.272) | 0.901 |
CI, confidence interval; HR, hazard ratio; IPTW, inverse probability of treatment weighting; LS, laparoscopic surgery; mCCI, modified Charlson comorbidity index; OS, open surgery; RS, robotic surgery.