Fig. 3.

Diagnostic value for peripheral blood RNA of N6-methyladenosine (m⁶A) alone or combination with carcinoembryonic antigen (CEA) and carbohydrate antigen 153 (CA153) to diagnose patients with breast cancer (BC). Receiver operating characteristic (ROC) curve analysis for m⁶A in the diagnosis of BC (A) and cutoff value of m⁶A for normal controls (NCs) and patients with BC (B). ROC curve analysis of m⁶A compared and combined diagnosis with CEA and CA153 (C) and cutoff value analysis for the combination of m⁶A, CEA, and CA153 in NCs and patients with BC (D). AUC, area under the curve.