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. 2020 Oct 27;53(2):399–408. doi: 10.4143/crt.2020.870

Table 1.

Association between the m6A contents and the clinicopathological characteristics in BC patients

Variable No. of patients Peripheral blood m6A contents mean±SD (%) p-value
Age (yr)
 < 50 22 0.141±0.070 0.795
 ≥ 50 40 0.141±0.080
TNM
 0 6 0.085±0.020 0.968
 I 10 0.166±0.096
 II 31 0.152±0.084
 III 6 0.143±0.021
 IV 2 0.190±0.042
Stage
 0 6 0.085±0.020 0.003
 I–IV 49 0.155±0.080
T category
 Tis 6 0.085±0.020 0.129
 T1–T2 41 0.155±0.086
 T3–T4 6 0.142±0.029
N category
 N0 35 0.135±0.078 0.078
 N1 15 0.171±0.085
 N2–N3 3 0.143±0.031
M category
 M0 53 0.146±0.079 0.174
 M1 2 0.190±0.042
TNBC
 Yes 8 0.150±0.068 0.72
 No 47 0.147±0.081
AFP (ng/mL)
 < 6 59 0.142±0.077 0.735
 ≥ 6 3 0.127±0.076
CEA (ng/mL)
 < 5 54 0.146±0.079 0.213
 ≥ 5 8 0.108±0.039
CA125 (IU/mL)
 < 35 55 0.141±0.079 0.649
 ≥ 35 7 0.140±0.049
CA153 (IU/mL)
 < 25 58 0.141±0.077 0.985
 ≥ 25 4 0.143±0.078

AFP, α-fetoprotein; BC, breast cancer; CA125, cancer antigen 125; CA153, carbohydrate antigen 153; CEA, carcinoembryonic antigen; m6A, N6-methyladenosine; SD, standard deviation; TNBC, triple-negative breast cancer.