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. 2021 Apr 5;118(15):e2102804118. doi: 10.1073/pnas.2102804118

Fig. 3.

Fig. 3.

Hematological and immunological profile of patients with inherited ZNFX1 deficiency. (A) Absolute numbers of peripheral total leukocytes, neutrophils, lymphocytes, monocytes and platelets, and hemoglobin from P1, P2, and P3, determined from complete blood counts. (B) UMAP analysis of CyTOF showing the distribution of the main peripheral leukocyte populations identified in a healthy control, P1, P2, and P3. (C) Frequency of living CD4+ T cells and their subsets in adult controls (green circles), age-matched controls (PedCtrls, blue circles), and P1, P2, and P3 (red circles), as determined by CyTOF. Frequency of living (D) CD8+ T cells and their subsets, (E) B cells, (F) γδ T cells, (G) NK cells and their subsets, and (H) MAIT cells, and frequency of (I) monocytes and their subsets, (J) eosinophils, (K) basophils, and (L) dendritic cells (DCs) and their subsets, as determined by CyTOF. Results are expressed as a proportion of living single PBMCs.