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. 2021 Feb 24;24:591–609. doi: 10.1016/j.omtn.2021.02.023

Figure 4.

Figure 4

circ_0001018 enhanced cell growth in TPC-1 and IHH-4 cells

(A) Cell survival was determined by a CCK-8 assay in TPC-1 and IHH-4 cells, in which circRNA-OE, sh-circRNA, miR-338-3p inhibitor, or sh-circRNA plus miR-338-3p inhibitor was transfected. OD450, optical density at 450 nm. Data indicate mean ± SD from at least three independent experiments and three repetitions. ∗∗p < 0.01, versus control; ##p < 0.01, versus sh-circRNA group. (B) An EdU assay was used to detect the cell proliferation in TPC-1 and IHH-4 cells, in which circRNA-OE, sh-circRNA, miR-338-3p inhibitor, or sh-circRNA plus miR-338-3p inhibitor was transfected.