Fig. 4.

Bioinformatics analysis of circFKBP8 and circMBNL1. (a) Possible binding of miRNAs and mRNAs to circFKBP8 and circMBNL1. Circles indicate circRNA, triangles indicate miRNA and squares indicate mRNA. Nodes highlighted in red and blue represent upregulation and downregulation, respectively. (b) The biological process of 10 mRNAs of ceRNA networks, identified from the Gene Ontology enrichment analysis of all significantly different mRNAs of the RNA sequencing. The above panel indicates up-regulated biological process in MDD and the bottom panel indicates down-regulated biological process in MDD. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)