Fig. 3.

Establishment of drug resistance score. (a) Schematic illustration of GRM score calculation based on Growth rate fitted curves of dose-response of PDAC cell lines treated with different drugs. (b to f) Ranking of cell lines from the most resistant to the most sensitive based on GRM scores respectively for gemcitabine, oxaliplatin, 5-FU, SN-38 and docetaxel. Red to green colours reflect the gradient of resistance/sensitivity to the drug. Scores were scaled and centered around zero.(For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)