Fig. 5.

(a) Heatmap of the hierarchical clustering based on the correlation of all identified metabolic features that were associated to at least one drug. Red and blue colors indicate positive and negative correlation, whereas the white color indicates the absence of correlation. (b) Scatterplots comparing the GRM scores among the three significantly correlated drugs; gemcitabine, oxaliplatin and 5-FU. (c) Graphic visualization of correlation matrix among GRM scores of the five drugs. The proportion of the pie chart indicates the level of correlation and the color indicates positive and negative correlation.(For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)