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. 2021 Apr 19;22:137. doi: 10.1186/s12882-021-02356-4

Table 2.

List of hub-DEGs, and topmost DEmiRs, TFs and lncRNAs in the constructed multilayer regulatory network

Type Name Degree Type Name Degree
DEGs TP53 112 lncRNAs HOTAIR 32
STAT3 73 MEG3 24
JUN 46 H19 21
FOS 43 MALAT1 20
DNMT1 38 UCA1 17
NOTCH1 37 CDKN2B-AS1 14
TGFB1 36 GAS5 10
E2F3 34 NEAT1 10
CREB1 34 PVT1 10
XIAP 34 HULC 9
SUMO1 33
VIM 32 TFs EZH2 74
ETS1 29 MYC 56
ABCB1 27 NF-κB 39
COX6B1 26 DEmiRs hsa-mir-16-5p 134
TERT 25 hsa-mir-92a-3p 108
CEBPB 25 hsa-let-7b-5p 105
CRK 24 hsa-mir-17-5p 102
TXNIP 24 hsa-mir-124-3p 97
CCNE1 22 hsa-mir-93-5p 95
FOXK1 22
SNRPD1 21
BAX 21
TAOK1 21
CRCP 21
BAX 21
TBL1XR1 20
HSP90AB1 20
Klf4 19
HNRNPA2B1 19