Table 1.
Anthropometric, biochemical and hormonal measurement (means + SD) of controls and PCOS subjects
| Clinical Variables | Control (n = 9) |
PCOS (n = 10) |
P-value |
|---|---|---|---|
| Age (years) | 24.8 ± 6.3 | 28.2 ± 7.1 | 0.29 |
| BMI (kg/m2) | 25.4 ± 5.8 | 29.9 ± 5.4 | 0.09 |
| Waist (cm) | 79.6 ± 13.6 | 91.7 ± 12.7 | 0.06 |
| Hip (cm) | 99.1 ± 14.7 | 109.9 ± 11.8 | 0.09 |
| WHR | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.24 |
| SBP (mmHg) | 117.3 ± 6.2 | 118.8 ± 10.2 | 0.71 |
| DBP (mmHg) | 74.2 ± 8.5 | 76.2 ± 7.8 | 0.60 |
| Free androgen index | 1.9 ± 2.1 | 6.6 ± 3.2 | 0.002 |
| SHBG (nmol/L) | 72.6 ± 29.8 | 26.0 ± 19.5 | 0.001 |
| Testosterone (nmol/L) | 0.9 ± 0.3 | 1.3 ± 0.6 | 0.12 |
| Total cholesterol (mmol/L) | 4.6 ± 0.8 | 4.1 ± 0.7 | 0.14 |
| Triglycerides (mmol/L) | 0.8 ± 0.2 | 1.3 ± 0.8 | 0.08 |
| HDL-c (mmol/L) | 1.5 ± 0.5 | 1.3 ± 0.4 | 0.29 |
| LDL-c (mmol/L) | 2.7 ± 0.6 | 2.3 ± 0.5 | 0.17 |
| ALT (IU/L) | 17.3 ± 5.8 | 29.8 ± 13.9 | 0.03 |
| FPG (mmol/L) | 4.7 ± 0.6 | 4.7 ± 0.5 | 0.93 |
| NEFA (μmol/L) | 505.2 ± 180.2 | 482.9 ± 144.4 | 0.77 |
| HOMA-IR | 1.4 ± 0.8 | 2.7 ± 1.7 | 0.05 |
Values are represented as means + SD
BMI Body Mass Index, WHR Waist Hip ratio, SBP Systolic blood pressure, DBP Diastolic blood pressure, SHBG Sex hormone binding globulin, TC Total cholesterol, LDL-c Low density lipoprotein cholesterol and HDL-c High density lipoprotein cholesterol and TG triglyceride, ALT alanine transferase, FPG fasting plasma glucose, NEFA non-esterified free fatty acids, HOMA-IR Homeostatic model assessment of insulin resistance
Student’s unpaired t-test was done between control and PCOS subjects
P < 0.05 is considered to be statistically significant