Table 3.
Univariate and Multivariate Analyses for Factors Associated with EE in the Pre-MS Group (n=964)
| Univariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | OR | 95% CI | p-value | |
| Sex (M/F) | 1.744 | 1.189–2.560 | < 0.005 | 1.446 | 0.965–2.166 | 0.074 |
| Age (years) | 1.000 | 0.985–1.016 | 0.966 | |||
| BMI (kg/m2) | 1.028 | 0.983–1.075 | 0.231 | |||
| WC (cm) | 1.000 | 0.979–1.022 | 0.983 | |||
| Smoking | 1.333 | 0.954–1.861 | 0.092 | |||
| Drinking | 1.539 | 1.138–2.081 | < 0.01 | 1.413 | 1.029–1.940 | < 0.05 |
| SBP (mmHg) | 0.999 | 0.990–1.008 | 0.827 | |||
| DBP (mmHg) | 1.003 | 0.991–1.016 | 0.589 | |||
| Hypertension | 1.070 | 0.787–1.453 | 0.667 | |||
| T-CHO (mg/dL) | 1.001 | 0.996–1.005 | 0.703 | |||
| TG (mg/dL) | 1.001 | 0.998–1.003 | 0.669 | |||
| HDL-C (mg/dL) | 1.001 | 0.991–1.012 | 0.852 | |||
| LDL-C (mg/dL) | 1.001 | 0.996–1.006 | 0.769 | |||
| Dyslipidemia | 0.768 | 0.543–1.087 | 0.137 | |||
| FPG (mg/dL) | 1.010 | 0.998–1.022 | 0.117 | |||
| HbA1c (%) | 1.225 | 0.740–2.029 | 0.430 | |||
| IGT | 1.497 | 0.910–2.460 | 0.112 | |||
| UA (mg/dL) | 1.038 | 0.937–1.151 | 0.475 | |||
| AST (IU/L) | 1.015 | 0.999–1.032 | 0.065 | |||
| ALT (IU/L) | 1.009 | 1.001–1.017 | < 0.05 | 1.007 | 0.998–1.015 | 0.114 |
| GGT (IU/L) | 1.000 | 0.996–1.003 | 0.928 | |||
| H. pylori | 0.504 | 0.310–0.817 | < 0.01 | 0.508 | 0.311–0.829 | < 0.01 |
| Hiatal hernia | 1.580 | 1.191–2.097 | < 0.005 | 1.480 | 1.111–1.972 | < 0.01 |
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CI, confidence interval; DBP, diastolic blood pressure; EE, erosive esophagitis; F, female; FPG, fasting plasma glucose; GGT, gamma-glutamyl transpeptidase; HbA1c, hemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; H. pylori, Helicobacter pylori; IGT, impaired glucose tolerance; LDL-C, low-density lipoprotein cholesterol; M, male; MS, metabolic syndrome; OR, odds ratio; SBP, systolic blood pressure; T-CHO, total cholesterol; TG, triglyceride; UA, uric acid; WC, waist circumference.