Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 5;38(8):1000–1005. doi: 10.1089/neu.2020.7039

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Gregory T. Bramblett et al., 2020; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

PMC Copyright notice

FIG. 1. — Distribution of plasma concentrations of traumatic brain injury (TBI) biomarkers before and after optic nerve (ON) crush. Post-injury concentrations of all biomarkers were significantly elevated compared with pre-injury concentrations. Whiskers represent the 10th and 90th percentiles. (A) Glial fibrillary acidic protein (GFAP): pre-injury median (interquartile range [IQR]) concentration is 7.76 pg/mL (5.48–15.3) and post-injury median (IQR) concentration is 52.3 pg/mL (32.3–53.4) (p < 0.01). (B) Ubiquitin c-terminal hydrolase L1 (UCH-L1): pre-injury median (IQR) concentration is 63.6 pg/mL (32.8–121.0) and post-injury median (IQR) concentration is 77.6 pg/mL (40.1–141.0) (p = 0.01). (C) Neurofilament light chain (NFL): pre-injury median (IQR) concentration is 11.8 pg/mL (8.89–14.8) and post-injury median (IQR) concentration is 13.9 pg/mL (11.0–17.5) (p < 0.01).