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Summary receiver operating characteristics plot of sensitivity and specificity of S100 calcium binding protein B (S100B) at a 0.10–0.11μg/L cutoff value for detecting intracranial lesions on CT. Each circle represents an individual study; size of the symbol reflects the number of patients in the studies; red solid spot in the middle is summary sensitivity and specificity; inner ellipse represents 95% confidence region, and outer ellipse represents 95% prediction region.
