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. 2020 Nov 20;162(5):1416–1425. doi: 10.1097/j.pain.0000000000002127

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Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association for the Study of Pain.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 1. — Hanging behavior is impaired in models of inflammatory and neuropathic pain. (A) The effect of injection of complete Freund's adjuvant (CFA) or spared nerve injury (SNI) on 8 distinct homecage behaviors of CD-1 mice was quantified using automated video scoring (CleverSys HomeCageScan). Data are shown as the percentage of time mice participated in each behavior over 24 hours (average ± SEM). Note that hanging behavior is reduced after both CFA and SNI, but only recovers to normal levels after CFA, not after SNI. *P < 0.05, **P < 0.01, ***P < 0.001 compared with baseline (−1).