Table 2.
Summary of patient data set at different time points: SBPs (skin-breaking procedure at 5 days), GA (gestational age in weeks), birth weight (in g), PMA (postmenstrual age in weeks) at different recording dates (5 days, 34w, PSG), CRIB score, APGAR score at 5 minutes from birth, and the number of days in mechanical ventilation and continuous positive airway pressure, caffeine treatment (number of patients receiving treatment, standard dose 5 mg/kg) at first and second EEG measurements, and the ultrasound evaluation.
| HIGH SBP (n = 19) | LOW SBPs (n = 73) | P | |
|---|---|---|---|
| SBPs | 60 [56.25-69.5] | 31 [24-37] | ≤0.01 |
| GA (weeks) | 26.57 [25.29-29.5] | 32 [29.5-32.57] | ≤0.01 |
| PMA at 5 days (first rec) | 28.57 [26.43-31.57] | 32.86 [31-33.57] | ≤0.01 |
| PMA at 34w (second rec) | 34.29 [33.71-34.29] | 34.07 [33.86-34.29] | 0.32 |
| PMA at PSG (third rec) | 39.93 [38.71-42] | 38.43 [37.36-39.21] | ≤0.01 |
| Birth weight (g) | 950 [820-1137.5] | 1540 [1230-1800] | ≤0.01 |
| CRIB score | 2 [1-4.75] | 0 [0-1] | ≤0.01 |
| APGAR 5 min | 8 [6.25-9] | 8 [6-8] | 0.14 |
| Days of mechanical ventilation | 2.5 [0-16.5] | 0 [0-0] | ≤0.01 |
| Days of CPAP | 41.5 [7.75-55.5] | 4 [2-28] | ≤0.01 |
| Caffeine (at 5 days) | 17 | 63 | 0.715 |
| Caffeine (at 34w) | 15 | 31 | ≤0.05 |
Data are split in HIGH SBP (SBP ≥50) and LOW SBP (SBP <50). Data are median [IQR] except for the caffeine treatment. Data were compared between the low and high SBP groups using Mann–Whitney U tests for continuous variables and χ2 tests for categorical variables.
SBP, skin-breaking procedures; PMA, postmenstrual age.