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. 2021 Apr 13;10(4):8. doi: 10.1167/tvst.10.4.8

Figure 5.

Figure 5.

L-DOPA treatment selectively recovers OP2 implicit time for rod-driven ERG responses. (A, B, C) Representative ERG recordings from each treatment group at 10 weeks after STZ for rod-driven and rod/cone-driven responses. (D) Average OP2 implicit times across time in response to rod-driven dim flash stimuli showed significant delays by 3 weeks, which recovered with daily L-DOPA treatment, three-way repeated-measure ANOVA, interaction effect of diabetes and treatment, F (1, 33) = 4.403, P = 0.0436. (E, F) OP2 implicit times in response to both dim and bright mixed rod/cone-driven stimuli showed significant delays by 3 weeks which were not altered by daily L-DOPA treatment (three-way repeated-measure ANOVA, main effect diabetes, F (1, 86) = 39.01, P < 0.0001 and F (1, 90) = 89.93, P < 0.0001, respectively). Data plotted as mean ± standard error of the mean. *P < 0.05; **P < 0.01.