Table I.

Significantly upregulated mRNAs following the overexpression of IRF1 according to RNA sequencing.

ID	Base mean	Base mean control sample NC	Base mean case sample Ad-IRF1	Fold change	log2 fold change	P-value	Adjusted P-value	Gene
IFI6	8362.5161	2804.2397	13920.7926	4.9642	2.3116	0	0	Up
BST2	131.2432	23.2430	239.2434	10.2931	3.3636	1.65×10−53	1.30×10−49	Up
TFF1	773.5291	480.7576	1066.3006	2.2180	1.1492	1.21×10−33	1.46×10−30	Up
ISG15	6329.8561	3499.2967	9160.4154	2.6178	1.3883	2.49×10−33	2.79×10−30	Up
TMEM238	432.1279	251.8244	612.4313	2.4320	1.2821	3.19×10−30	3.13×10−27	Up
RARRES3	247.1411	136.0866	358.1957	2.6321	1.3962	4.76×10−23	2.49×10−20	Up
LRRC26	240.0970	139.0721	341.1219	2.4528	1.2945	1.11×10−19	3.49×10−17	Up
NUPR1	192.9297	105.5262	280.3331	2.6565	1.4095	5.60×10−19	1.60×10−16	Up
IFITM1	180.7444	76.9545	284.5344	3.6974	1.8865	9.90×10−18	2.35×10−15	Up
C4orf48	1337.1611	856.0667	1818.2556	2.1240	1.0868	1.55×10−16	2.94×10−14	Up
IFI35	245.9523	159.7153	332.1892	2.0799	1.0565	4.29×10−14	5.26×10−12	Up
SPINK4	609.8811	393.3366	826.4257	2.1011	1.0711	6.25×10−13	5.89×10−11	Up
CBR3	210.2773	138.8154	281.7391	2.0296	1.0212	7.98×10−12	5.91×10−10	Up
GADD45G	154.6964	90.6289	218.7639	2.4138	1.2713	2.96×10−11	1.94×10−9	Up
MRPL23	4537.9171	3004.8832	6070.9510	2.0204	1.0146	6.21×10−11	3.68×10−9	Up
MYH4	32.3621	10.9477	53.7765	4.9121	2.2964	4.95×10−9	1.73×10−7	Up
SMIM22	619.3599	411.7948	826.9250	2.0081	1.0058	6.72×10−9	2.28×10−7	Up
LGALS9	34.6546	12.7458	56.5634	4.4378	2.1498	1.10×10−8	3.55×10−7	Up
TSTA3	174.7754	109.1525	240.3983	2.2024	1.1391	7.56×10−8	1.96×10−6	Up
SHD	34.9248	14.7999	55.0497	3.7196	1.8951	2.99×10−7	6.68×10−6	Up

Ad, adenovirus expression vector; IRF1, interferon regulatory factor 1; NC, negative control.