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. 2020 Jul 23;41(5):958–974. doi: 10.1177/0271678X20942613

Figure 1.

Figure 1.

Neurological dysfunction in Cx3cr1CreER:Hdac2fl/fl and WT mice after ICH. (a–d) Sensorimotor dysfunction was significantly alleviated in Cx3cr1CreER:Hdac2fl/fl mice at the early phase after ICH. The Morris water maze test was performed to measure cognitive deficits after ICH (e–g). (e) Representative swim path from each treatment group during the spatial learning (top panel) and memory phage (bottom panel) of the Marris water maze test. (f) Latency to find the hidden platform in the cued learning response 28 to 32 days after ICH (spatial learning). (g) The total distance in the same quadrant as the platform after training in sham groups (WT and HDAC2 çKO mice) and ICH groups (WT and HDAC2 çKO mice). n = 10–12/group. *p ≤ 0.05, **p ≤ 0.01 vs. WT ICH; #p ≤ 0.05, ##p ≤ 0.01, ###p ≤ 0.001 vs. sham group. All data are presented as mean ± SD.