Figure 5.

Scriptaid improves neurological function recovery after ICH. (a–d) Sensorimotor dysfunction was significantly alleviated in scriptaid-treated mice at the early phase after ICH. (e–f) The Morris water maze test was performed to measure cognitive deficits after ICH. (e) Representative swim path from each treatment group during the spatial learning (top panel) and memory phage (bottom panel) of the Marris water maze test. (f) Latency to find the hidden platform in the cued learning response 28 to 32 days after ICH (spatial learning). (g) The totally distance in the same quadrant as the platform after training for mice in sham, vehicle and scriptaid-treated groups. n = 10–12/group. *p ≤ 0.05, **p ≤ 0.01, *** p ≤ 0.001 vs. vehicle group; ^#p ≤ 0.05, ^##p ≤ 0.01, ^###p ≤ 0.001 vs. sham group. All data are presented as mean ± SD.