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. Author manuscript; available in PMC: 2021 Apr 19.

Published in final edited form as: Oncogene. 2018 Feb 28;37(20):2630–2644. doi: 10.1038/s41388-017-0122-y

Table 1.

Penetrance and latencies of experimental cohorts

Injected myoblasts				Host mice	Tumors
		Transgene			Penetrance (n)	Mean latency (weeks)	Median latency (weeks)
Parental cell line	Genotype	Right limb	Left limb	Genotype		(Range)
Myo25	p53^−/−	FGFR4^wt	Empty vector	p53^+/−, p53^+/+	71%	34.7	36.9
					(5/7)	(19–51 weeks)
Myo25	p53^−/−	FGFR4^N535K	FGFR4^wt	p53^+/−	9%	12.9	12.9
					(1/11)	—
Myo25	p53^−/−	FGFR4^V550E	FGFR4^wt	p53^+/−	92%	11.9	10.6
					(11/12)	(9–26 weeks)
Myo25	p53^−/−	—	Empty vector	p53^+/−	—	—	—
					(0/10)	—	—