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. Author manuscript; available in PMC: 2021 Apr 19.
Published in final edited form as: Oncogene. 2018 Feb 28;37(20):2630–2644. doi: 10.1038/s41388-017-0122-y

Table 1.

Penetrance and latencies of experimental cohorts

Injected myoblasts
Host mice Tumors
Transgene
Penetrance (n) Mean latency (weeks) Median latency (weeks)
Parental cell line Genotype Right limb Left limb Genotype (Range)
Myo25 p53−/− FGFR4wt Empty vector p53+/−, p53+/+ 71% 34.7 36.9
(5/7) (19–51 weeks)
Myo25 p53−/− FGFR4N535K FGFR4wt p53+/− 9% 12.9 12.9
(1/11)
Myo25 p53−/− FGFR4V550E FGFR4wt p53+/− 92% 11.9 10.6
(11/12) (9–26 weeks)
Myo25 p53−/− Empty vector p53+/−
(0/10)