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. 2021 Apr 16;23(4):e26645. doi: 10.2196/26645

Table 4.

Estimates of and factors associated with serial interval based on 558 infector-infectee pairs.

Factors Pairs, n (%) Subgroup-specific estimates (95% empirical CI) Percentage contribution (95% CI)
Age group of infector (years)

0-30 77 (13.8) 4.12 (3.41, 4.83) Referencec

31-45 121 (21.7) 4.43 (3.53, 5.33) –0.24 (–16.50, 17.88)

46-60 179 (32.1) 4.84 (4.26, 5.43) 10.47 (–6.17, 28.92)

≥61 181 (32.4) 5.12 (4.42, 5.82) 7.57 (–9.28, 26.33)
Sex of infector

Female 295 (52.9) 4.83 (4.34, 5.33) Referencec

Male 263 (47.1) 4.64 (4.10, 5.18) –5.52 (–14.81, 4.37)
Presence of chronic conditions among infectors

No 485 (86.9) 4.58 (4.20, 4.95) Referencec

Yes 73 (13.1) 5.85 (4.57, 7.13) 0.41 (–15.17, 17.67)
Number of general symptoms presented by infectors

0 338 (60.6) 4.78 (4.32, 5.25) Referencec

≥1 220 (39.4) 4.69 (4.09, 5.28) –6.34 (–16.48, 4.53)
Number of respiratory symptoms presented by infectors

0 336 (60.2) 4.22 (3.83, 4.61) Referencec

≥1 222 (39.8) 5.54 (4.84, 6.23) 8.29 (–3.07, 20.48)
Type of setting

Household 390 (69.9) 4.83 (4.41, 5.25) Referencec

Institution 10 (1.8) 5.00 (2.59, 7.41) 4.05 (–30.27, 47.56)

Social activity 113 (20.3) 4.27 (3.54, 4.99) –9.17 (–20.78, 3.41)

Work 45 (8.1) 5.16 (3.12, 7.19) –4.00 (–21.02, 15.12)
Wave

1 94 (16.8) 6.70 (5.45, 7.95) Referencec

2 464 (83.2) 4.35 (4.00, 4.70) –33.90 (–45.08, –21.63)
Order of transmission

Secondary 445 (79.7) 4.89 (4.49, 5.30) Referencec

Tertiary 102 (18.3) 4.36 (3.46, 5.27) –17.31 (–28.84, –4.75)

Quaternary or beyond 11 (2) 2.18 (–0.52, 4.88) –50.75 (–72.53, –23.45)
Relative mobility indexa,b,c N/Ad N/A 0.83 (0.32, 1.33)

aAn 8-day lag was assumed to account for the time between exposure to SARS-CoV-2 and the first symptom onset, based on the estimated 7.76-day incubation period [21].

bThe original mobility index was further adjusted relative to January 18, 2020, which has a value of 100.

cThe reference is a common comparator across all variables.

dN/A: not applicable.