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. 2021 Apr 16;23(4):e25852. doi: 10.2196/25852

Table 3.

Prediction model and performance for the modified clinical severity score.

Response Variable selection method Variables, n Sample size Model Training Testing



Training Testing
Area under the curve Sensitivity Specificity Area under the curve Sensitivity Specificity
y1a Stepwise 16 2643 1331 Logistic regression 0.865 0.831 0.745 0.853 0.775 0.797
Random forest 0.958 0.888 0.888 0.841 0.765 0.792
Support vector machine 0.87 0.783 0.806 0.856 0.83 0.75
y1 Least absolute shrinkage and selection operator 5 2686 1354 Logistic regression 0.85 0.755 0.794 0.847 0.745 0.812
Random forest 0.905 0.767 0.847 0.83 0.71 0.843
Support vector machine 0.854 0.77 0.787 0.848 0.739 0.84
y2b Stepwise 14 2931 1459 Logistic regression 0.891 0.803 0.807 0.864 0.82 0.765
Random forest 0.901 0.832 0.85 0.834 0.757 0.837
Support vector machine 0.887 0.834 0.771 0.854 0.868 0.687
y2 Least absolute shrinkage and selection operator 6 2683 1348 Logistic regression 0.881 0.757 0.832 0.877 0.812 0.793
Random forest 0.943 0.87 0.841 0.865 0.772 0.842
Support vector machine 0.886 0.835 0.768 0.879 0.812 0.816
y3c Stepwise 11 2931 1460 Logistic regression 0.939 0.952 0.795 0.94 0.982 0.766
Random forest 0.931 0.871 0.925 0.863 0.807 0.91
Support vector machine 0.933 0.944 0.789 0.935 0.842 0.895
y3 Least absolute shrinkage and selection operator 6 2691 1357 Logistic regression 0.923 0.86 0.873 0.944 0.884 0.88
Random forest 0.991 0.984 0.949 0.933 0.895 0.865
Support vector machine 0.918 0.812 0.918 0.943 0.874 0.906

ay1: mild vs above moderate.

by2: below oderate vs above severe.

cy3: below severe vs critical.