Table 3.
Characteristics of adult patients on RRT with and without SARS-CoV-2 infection
| Population | Patients on Hemodialysis, n=4297 | Kidney Transplant Recipients, n=3293 | ||||
|---|---|---|---|---|---|---|
| COVID-19 Positive, % (No.) | COVID-19 Negative, % (No.) | P Value | COVID-19 Positive, % (No.) | COVID-19 Negative, % (No.) | P Value | |
| Total no. | 228 | 4069 | 46 | 3247 | ||
| Age, yr | P=0.26 | P=0.78 | ||||
| 25–44 | 2.2 (5) | 4.6 (186) | 13.0 (6) | 13.5 (439) | ||
| 45–64 | 16.7 (38) | 17.2 (701) | 52.2 (24) | 44.7 (1452) | ||
| 65–74 | 19.3 (44) | 21.5 (873) | 23.9 (11) | 30.2 (979) | ||
| 75–84 | 36.0 (82) | 35.3 (1437) | 8.7 (4) | 10.5 (341) | ||
| 85+ | 25.9 (59) | 21.4 (872) | 2.2 (1) | 1.1 (36) | ||
| Sex | P=0.03 | P=0.55 | ||||
| Men | 53.9 (123) | 61.4 (2497) | 56.5 (26) | 61.0 (1981) | ||
| Women | 46.1 (105) | 38.6 (1572) | 43.5 (20) | 39.0 (1266) | ||
| Diagnosis | ||||||
| ARF | 1.3 (3) | 2.5 (100) | P=0.37 | 0.0 (0) | 0.9 (30) | P>0.99 |
| Cardiorenal syndrome | 5.7 (13) | 7.2 (292) | P=0.51 | 0.0 (0) | 0.2 (7) | P>0.99 |
| ADPKD | 6.1 (14) | 5.2 (212) | P=0.54 | 13.0 (6) | 19.9 (647) | P=0.35 |
| Type 1 diabetes | 5.3 (12) | 2.0 (83) | P=0.004 | 0.0 (0) | 5.7 (184) | P=0.11 |
| Type 2 diabetes | 25.0 (57) | 18.7 (762) | P=0.02 | 4.3 (2) | 4.8 (157) | P>0.99 |
| Hereditary diseases | 2.2 (5) | 1.2 (47) | P=0.20 | 4.3 (2) | 3.8 (124) | P=0.70 |
| Glomerular diseases | 8.3 (19) | 14.6 (593) | P=0.008 | 37.0 (17) | 28.3 (918) | P=0.19 |
| Hypertension/RVD | 27.2 (62) | 23.5 (958) | P=0.23 | 8.7 (4) | 8.5 (275) | P=0.79 |
| TID | 8.8 (20) | 9.8 (400) | P=0.73 | 19.6 (9) | 14.6 (474) | P=0.40 |
| Miscellaneous | 2.6 (6) | 6.1 (250) | P=0.03 | 0.0 (0) | 3.8 (125) | P=0.42 |
| Unknown | 7.5 (17) | 9.1 (372) | P=0.48 | 13.0 (6) | 9.4 (306) | P=0.44 |
| Comorbid conditions | ||||||
| Diabetes mellitus | 51.3 (117) | 39.8 (1618) | P<0.001 | 10.9 (5) | 14.0 (451) | P=0.67 |
| CVD | 57.2 (123) | 55.7 (2053) | P=0.31 | NA | NA | |
| BMI≥30 kg/m2 | 37.3 (81) | 28.2 (1047) | P=0.002 | NA | NA | |
| Nursing home residence | 11.7 (24/205) | 4.9 (173/3495) | P<0.001 | NA | NA | |
| Total RRT vintage | P=0.008 | P=0.003 | ||||
| 0–6 mo | 13.2 (30) | 8.2 (333) | 2.2 (1) | 0.1 (4) | ||
| 7–12 mo | 8.8 (20) | 9.5 (387) | 0.0 (0) | 0.5 (16) | ||
| 1.0–2.4 yr | 21.1 (48) | 26.4 (1074) | 8.7 (4) | 3.1 (100) | ||
| 2.5–4.9 yr | 26.8 (61) | 25.9 (1054) | 6.5 (3) | 10.8 (352) | ||
| 5.0–9.9 yr | 23.7 (54) | 18.9 (769) | 23.9 (11) | 27.4 (891) | ||
| 10+ yr | 6.6 (15) | 11.1 (452) | 58.7 (27) | 58.0 (1884) | ||
Hereditary diseases excludes patients with ADPKD. Cardiovascular disease was defined as presence of at least one of the following at the start of RRT: congestive heart failure, ischemic heart disease, peripheral vascular disease, cerebrovascular disease. Total RRT vintage was calculated from the first day of any form of RRT. ADPKD, autosomal dominant polycystic kidney disease; RVD, renal vascular disease; TID, tubulointerstitital disease; CVD, cardiovascular disease; NA, not available; BMI, body mass index.