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. 2021 Apr 19;16(4):e0250091. doi: 10.1371/journal.pone.0250091

Table 1. Baseline characteristics of the included studies.

studies tumor type treatment region sample Inclusion period NLR/time obtained outcomes NOS
Albisinni 2019 [15] bladder cancer CR Belgium 134 2013–2018 5.58/ 1 month OS, DFS 8
Bojaxhiu 2018 [16] head and neck cancer R, RC Switzerland 186 2007–2010 3.28/ <10 days OS, DFS 6
Cui 2020 [17] colorectal cancer R China 146 2011–2014 2.96/≥7 days DFS 7
Guo 2018 [18] colorectal cancer R China 135 2009–2014 3.64/>1 month OS, DFS 7
Hayama 2020 [19] colorectal cancer CR Japan 176 2012–2016 3.1/ 7th day DFS 6
He 2017 [20] synchronous colorectal cancer CR China 114 2009–2013 10.5/≤3 days OS, DFS 6
Hoshimoto 2020 [21] pancreatic cancer R Japan 211 1995–2016 1.8/ 18–86 days OS 7
Jakubowska 2020 [22] colorectal cancer R Poland 144 2014–2016 3.3/ 3 days DFS 6
Jang 2017 [23] prostate cancer CR Korea 2302 2000–2010 3.5/ 2–3 months OS 7
Jin 2016 [24] non-small cell lung cancer R China 123 2007–2010 3.9/ >1 month OS, DFS 8
Kang 2016 [9] bladder cancer CR Korea 385 1999–2012 2/ 3–4 month OS 7
Kim 2019 [25] pancreas adenocarcinoma CRC Korea 178 2010–2018 2.535/ 1 months OS, DFS 6
Kim 2012 [26] stomach cancer R Korea 93 2004–2009 7.7/ third day DFS 8
Li 2018 [27] colon cancer CR China 344 2012–2015 3/ 1–3 months OS 6
Lin 2019 [28] oropharyngeal cancer R/RR USA 108 1997–2017 6.2/ 3 months OS, DFS 6
Lin 2018 [29] palatine tonsil cancer RR USA 99 1997–2013 11.875/<2.5 months OS 6
Miyatani 2018 [30] gastric cancer CR Japan 280 2001–2013 1.8/ 1 month OS 6
Nishihara 2019 [31] upper tract urothelial carcinoma CR Japan 134 2004–2015 2.5/ 1–2 month OS 8
Ohno 2012 [32] clear cell renal cell carcinoma R Japan 250 1990–2008 2.7/ 3 months DFS 6
Paik 2014 [33] colorectal cancer R Korea 600 2006–2009 5/ NA OS 7
Pu 2019 [34] pancreatic ductal adenocarcinoma R China 97 2012–2016 14.1/ NA OS, DFS 7
Shibutani 2015 [35] colorectal cancer CR Japan 254 2006–2011 3/ 29 (23–36) days OS 7
Tanaka 2018 [36] gastric cancer RC Japan 170 2006–2015 1.99/ NA DFS 6
Zhou 2016 [10] gastric cancer CR/CRC China 360 2006–2008 6.19/≥5 days OS 8
Zhou 2018 [37] colorectal cancer R China 516 2007–2015 2.41/ 1 month OS, DFS 7

CR, curative resection; CRC, curative resection and chemotherapy; R, resection; RR, resection and radiotherapy; RC, resection and chemotherapy; NLR, neutrophil-lymphocyte ratio; OS, overall survival; DFS, disease-free survival; NOS, Newcastle–Ottawa scale; NA, not available.