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. 2021 Apr 7;17(4):e1008977. doi: 10.1371/journal.ppat.1008977

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© 2021 Kumar et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 6 — A. Schedule of prime, boost and bleed time points. The binding (B) and neutralization of sequence matched (with and without N332) autologous viruses (C and D) by sera collected from four rabbits at 1:20 dilutions collected at different time points following prime and boost. E. Dose-dependent neutralization of pseudotyped virus expressing sequenced matched env (PG80v1.eJ19) by sera collected at week 22 following second boost with 1PGE-THIVC. F. Neutralization of pseudoviruses expressing sequence matched (PG80v1.eJ19) and unmatched (PG80v2.eJ38) autologous envs and heterologous tier1 envs (SF162 and 93IN905) by purified serum IgG in a dose-dependent manner; G. Binding of purified serum IgG (week 22; rabbit#1) to 1PGE-THIVC SOSIP trimer by D-7324 sandwich ELISA.