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. Author manuscript; available in PMC: 2021 Apr 19.
Published in final edited form as: Ann Cancer Epidemiol. 2021 Mar 30;5:2. doi: 10.21037/ace-19-40

Figure 1.

Figure 1

Conceptual framework of multiple primary cancers etiology: hypothesized involvement of genetic, environmental, and lifestyle risk factors in etiology of synchronous cancers; and the role of treatment and lifestyle in etiology of metachronous cancers.