Table 3.

Significant upstream regulators identified in SNCA-OVX mice (supplementary Excel sheet)

Upstream regulator	Pathway enrichment –log (p)
MAPT	−6.627
FMR1	−6.235
SOD1	−6.168
APP	−5.587
GLDN	−5.266
NRCAM	−5.266
PSEN1	−5.095
TP53	−4.833
REST	−4.481
ADAM10	−4.382
NFASC	−3.745
HTT	−3.638
MKNK1	−3.603
MYC	−3.545
RICTOR	−3.327
RANBP9	−3.037
SLC12A6	−3.037
ELAVL3	−3.037