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. 2021 Apr 21;41(16):3610–3621. doi: 10.1523/JNEUROSCI.1498-20.2021

Figure 2.

Figure 2.

Inhibitory neurons are postsynaptic partners of MCPO LRGNs in the OB. A, Top drawings, Example of distinct reconstructed neurons after recording: 1, GC; 2, MC; 3, TC; 4, PGC; 5, EPL-I. The morphology of the neurons was reconstructed from confocal images of fixed cells that were filled with AlexaFluor-594 during the recordings. Bottom, Example of eIPSCs recorded at −70 mV in symmetrical chloride conditions, on stimulation of GABAergic axons expressing ChR2 with blue light (5 ms). LED stimulation elicited large inward currents in GC, PGC, and EPL-I, but not in output neurons, the MC or TC. B, Bar graph represents the total charge transferred during the GABAergic eIPSCs in distinct cell types in the OB (GC, n = 16; MC, n = 11; PGC, n = 5; TC, n = 10; EPL-I, n = 3). Responses are observed in the main inhibitory types, but not in the output neurons.