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. 2021 Apr 15;13:3293–3301. doi: 10.2147/CMAR.S299563

Table 2.

Characteristics of Patients in the Two Groups and with the X2 Test for Categorical Variables

Characteristics Single-Site Radiotherapy Multiple-Site Radiotherapy P
Age(y) 57 (50–64) 52 (47.75–59.25) 0.002
 >60 47 (42.3) 21 (22.3)
 ≤60 64 (57.7) 73 (77.7)
Sex 0.808
 Female 75 (67.6) 65 (69.1)
 Male 36 (32.4) 29 (30.9)
Smoking Status 0.458
 Never 85 (76.6) 76 (80.9)
 Former/current 26 (23.4) 18 (19.1)
EGFR Mutation 0.264
 Exon 18 1 (0.9) 3 (3.2)
 Exon 19 55 (49.5) 37 (39.4)
 Exon 20 0 (0.0) 1 (1.1)
 Exon 21 55 (49.5) 52 (55.3)
 Exon 18 and 20 0 (0.0) 1 (1.1)
Systemic Therapy
 Platinum treatment 80 (72.1) 78 (83.0) 0.064
 First-line EGFR TKIs therapy 74 (66.7) 56 (59.6) 0.294
 Second-line EGFR TKIs therapy 37 (33.3) 38 (40.4) 0.294
Location of Metastasis
 Brain 68 (61.3) 70 (74.5) 0.045
 Bone 84 (75.7) 77 (81.9) 0.278
 Abdomen 2 (1.8) 11 (11.7)
 Soft tissue 1 (0.9) 0 (0.0)
The Site of Radiotherapy
 Thoracic 20 (18.0) 81 (86.2) <0.001
 Brain 48 (43.2) 65 (69.1) <0.001
 Bone 42 (37.8) 54 (57.4) 0.005
 Adrenal 2 (1.8) 6 (6.4)
 Liver 0 (0.0) 4 (4.3)
 Spleen 0 (0.0) 1 (1.0)
 Soft tissue 1 (0.9) 0 (0.0)
Number of Radiotherapy
 1 111 (100.0) 0 (0.0)
 2 0 (0.0) 71 (75.5)
 3 0 (0.0) 20 (21.3)
 4 0 (0.0) 3 (3.2)

Note: Data are presented as n (%) or median (interquartile range).

Abbreviations: EGFR, epidermal growth factor receptor; TKI, tyrosine kinase inhibitor.