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. 2021 Mar 30;96(13):e1732–e1742. doi: 10.1212/WNL.0000000000011555

Figure 2. Mendelian Randomization Associations of Genetically Predicted Insulin Resistance and β-Cell Dysfunction With Stroke Subtypes.

Figure 2

(A) Results derived from random-effects inverse-variance weighted analyses. (B) Heatmap of the associations between clusters of diabetic endophenotypes related to β-cell dysfunction and insulin resistance with the risk of stroke subtypes. Full colored circles in A correspond to statistically significant association estimates at a false discovery rate (FDR)–adjusted p value < 0.05. CI = confidence interval.