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. 2021 Apr 14;14:1647–1661. doi: 10.2147/DMSO.S301068

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© 2021 Ben et al.

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Effect of AS-IV on apoptosis.

Notes: (A and B) The results of TUNEL staining. Scale bar, 50 µm. (C) Immunohistochemical staining of cleaved caspase-3. Scale bar, 50 µm. (D) The cleaved caspase-3 expression was measured by Western blot. Data are represented as mean ± SD. *P < 0.05, ***P < 0.001 vs control group. ^###P < 0.001, ^#P < 0.05 vs DPN group.

Abbreviations: TUNEL, terminal deoxynucleotidyl nick-end labeling; SD, standard deviation; DPN, diabetic peripheral neuropathy; AS-IV, astragaloside IV; ALA, α-lipoic acid.