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. 2021 Apr 14;14:1647–1661. doi: 10.2147/DMSO.S301068

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© 2021 Ben et al.

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Western blot analysis of SIRT1, acetyl-p53, Drp1, BAX, BCL-2.

Notes: (A) Films of SIRT1, acetyl-p53, Drp1, BAX, BCL-2, and β-actin bands. (B–D) Levels of SIRT1 (B), acetyl-p53 (C), Drp1 (D) expressed as the optical density value normalized to β-actin. (E) Ratio of optical density value of BAX to BCL-2. Data are represented as mean ± SD. *P < 0.05, ***P < 0.001 vs control group. ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs DPN group.

Abbreviations: SD, standard deviation; DPN, diabetic peripheral neuropathy; AS IV, astragaloside IV; ALA, α-lipoic acid.