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. 2021 Apr 10;2021:6640751. doi: 10.1155/2021/6640751

Figure 4.

Figure 4

FSTL-1-knockdown mice had reduced levels of inflammatory cytokines in the IVDs. (a) The protein levels of iNOS, COX-2, MMP-13, and ADAMTS-5 in the disc tissues after puncture in WT and FSTL-1+/- mice. (b–e) Relative density of iNOS, COX-2, MMP-13, and ADAMTS-5 by Western blotting. (f–i) mRNA levels of iNOS, COX-2, MMP-13, and ADAMTS-5 in disc tissues after puncture in WT and FSTL-1+/- mice. The values are the mean ± SD of at least 3 independent experiments; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.