Table 1.
Distribution of study cases on the basis of their hemoglobin disorders.
| Genotypes | Hemoglobin disorders | Pediatric population (n = 1102) number | Adult population (n = 1230) number | Total (n = 2332) number |
|---|---|---|---|---|
| Normal | Normal β globin (AA) | 404 | 514 | 918 |
| Heterozygous state | Sickle cell trait (AS) | 254 | 281 | 535 |
| β-Thalassemia trait (Aβ) | 37 | 119 | 156 | |
| Hemoglobin D-Punjab trait (AD-Punjab) | 1 | 0 | 1 | |
| Heterozygous for high P2 (AP2) | 0 | 2 | 2 | |
| Heterozygous for high P3 (AP3) | 3 | 0 | 3 | |
| Hemoglobin E trait (AE) | 2 | 9 | 11 | |
| Heterozygous for high HbF (AF) | 27 | 1 | 28 | |
| Lepore trait (AL) | 0 | 8 | 8 | |
| Homozygous state | β-Thalassemia major (ββ) | 25 | 0 | 25 |
| Sickle cell anemia (SS) | 274 | 243 | 517 | |
| Homozygous for high HbF (FF) | 2 | 1 | 3 | |
| Double heterozygous state | HbE and β-thalassemia (Eβ) | 1 | 3 | 4 |
| Sickle cell and β-thalassemia (Sβ) | 34 | 41 | 75 | |
| Sickle cell and Lepore (SL) | 1 | 5 | 6 | |
| Sickle cell and hemoglobin E (SE) | 2 | 0 | 2 | |
| Lepore and β-thalassemia (Lβ) | 1 | 3 | 4 |
The hemoglobin disorders of 34 infants (<6 mo of age) were not analyzed though they were included in the pediatric population.