Table 1. Current overview of COVID-19 severity or mortality prediction models.
Author/setting/outcome | Score variables | Sample size (No. of participants for validation set) | Predictive performance |
---|---|---|---|
Liang et al.4/data from China, patients with confirmed COVID-19/in-hospital mortality | 10 variables (chest radiographic abnormality, age, hemoptysis, dyspnea, unconsciousness, number of comorbidities, cancer history, neutrophil-to-lymphocyte ratio, lactate dehydrogenase, direct bilirubin) | 1,590 (710) | C index 0.88 (95% CI, 0.84–0.93) |
Altschul et al.5/data from US, patients with confirmed COVID-19/in-hospital mortality | 6 variables (age, oxygen saturation, mean arterial pressure, blood urea nitrogen, C-Reactive protein, international normalized ratio) | 4,711 (2,356) | C index 0.80 (95% CI, 0.79–0.82) |
Gao et al.6/data from China, patients with confirmed COVID-19/in-hospital mortality | 14 variables (age, sex, fever, sputum, consciousness, respiration rate, oxygen saturation, chronic kidney disease, number of comorbidities, platelet, blood urea nitrogen, D-dimer, albumin, lymphocyte) | 2,520 (1,080) | C index 0.96 (95% CI, 0.95–0.98) |
Yadaw et al.9/data from US, patients with confirmed COVID-19/in-hospital mortality | 3 variables (age, minimum oxygen saturation, type of patient encounter) | 3,841 (1,210) | C index 0.91 (95% CI, 0.88–0.94) (retrospective), 0.94 (95% CI, 0.90–0.97) (prospective) |
COVID-19 = coronavirus disease 2019, CI = confidence interval.