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. 2021 Apr 8;7(4):e06668. doi: 10.1016/j.heliyon.2021.e06668

Table 1.

Top 10 Multi-functional Peptides in the FermFooDB with starter cultures.

Peptide Sequence Activities Starter Cultures Food
YP Ace-inhibitory, Antagonistic, Anti-hypertensive, Anti-microbial, Antibacterial, Antioxidant, Opioidantagonist, Cholesterol-lowering, Cytomodulatory, Immunomodulatory, Opioid, Opioid-agonist, Opioid-antagonist Lactobacillus helveticus CPN4 Yogurt Like product
FP Ace-inhibitory, Anti-hypertensive, Anti-microbial, Antibacterial, Antioxidant, Antithrombotic, CasoxinC (Opioidantagonist), Cholesterol-lowering, Cytomodulatory, Immunomodulatory, Mitogene, Opioid, Opioid-agonist Lactococcus lactis subsp. lactis (80%) and Leuconostoc mesenteroides subsp. dextranicum (20%), Raw Ewe's milk, Manchego cheese
PFP Ace-inhibitory, Anti-hypertensive, Anti-microbial, Antibacterial, Antioxidant, Antithrombotic, Cholesterol-lowering, Cytomodulatory, Immunomodulatory, Mitogene, Opioid, Opioid-agonist WSE of commercial manchego cheese (ewe's milk)
VP Ace-inhibitory, Anti-hypertensive, Anti-inflammatory, Anti-microbial, Antioxidant, Attenuate hepatitis, Cholesterol-lowering, Immunomodulatory, Intestinal protection, LOX inhibitor A. sojae Fermented Soybean Seasoning
QEPV Ace-inhibitory, Anti-hypertensive, Anti-inflammatory, Anti-microbial, Antibacterial, Antioxidant, Antithrombotic, Cholesterol-lowering, Immunomodulatory, Mitogene Lactobacillus paracasei subsp. paracasei BGHN14 Beta casein
PQ Ace-inhibitory, Anti-hypertensive, Anti-microbial, Antibacterial, Antioxidant, Antithrombotic, Cholesterol-lowering, Immunomodulatory, LOX inhibitor, Opioid Water soluble Extract (WSE) of commercial mahon cheese (cow milk)
PK Ace-inhibitory, Anti-hypertensive, Anti-microbial, Antibacterial, Antioxidant, Antithrombotic, Cytomodulatory, Immunomodulatory, Intestinal protection, Opioid WSE of commercial mahon cheese (cow milk)
VRGPFPIIV Ace-inhibitory, Anti-hypertensive, Anti-microbial, Antibacterial, Antioxidant, Antithrombotic, Cholesterol-lowering, Immunomodulatory, Mitogene Enterococcus faecalis CECT5727 Milk
VRGPFP Ace-inhibitory, Anti-hypertensive, Anti-microbial, Antibacterial, Antioxidant, Antithrombotic, Cholesterol-lowering, Immunomodulatory, Mitogene Lactococcus lactis subsp. lactis (80%) and Leuconostoc mesenteroides subsp. dextranicum (20%), Raw Ewe's milk, Manchego cheese
VRGP Ace-inhibitory, Anti-hypertensive, Anti-microbial, Antibacterial, Antioxidant, Antithrombotic, Cholesterol-lowering, Immunomodulatory, Mitogene WSE of commercial goat cheese