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Combination of CMR results with monoclonal protein studies (MPS)
| Characteristic LGE indicative of CA + negative MPS | LGE pattern NOT indicative of CA and/or positive MPS | Sensitivity and specificity (CI), % | PPV and NPV (CI), % | |
|---|---|---|---|---|
| EMB-proven presence of ATTR-CA, N = 92 | 83 | 9 | 90 (82–95) sensitive | NPV = 88 (80–93) |
| EMB negative for ATTR-CA, N = 68 | 1 | 67 | 99 (92–100) specific | PPV = 99 (92–100) |
