Cecectomy Causes Prolonged Increases in Energy Retention. (A) Body mass before surgery. (B) Body mass immediately after surgery. (C) Change in body mass after surgery. PSurgery=.008, PTime<.001, PInteraction=.007, PSubject<.001. (D) Calories ingested per day. PSurgery=.846, PTime=.421, PInteraction=.191, PSubject=.408. (E) Digestive efficiency. PSurgery=.014, PTime=.131, PInteraction=.030, PSubject=.001. (F) Calories absorbed per day. PSurgery=.403, PTime=.575, PInteraction=.166, PSubject=.250. (G) Energy efficiency. PSurgery=.005, PTime<.001, PInteraction=.014, PSubject=.001. For all panels, n = 9 male C57BL/6J mice per group, maintained on Envigo 7913 chow, with surgery performed at 13 weeks of age, and reported P-values calculated by two-way RM ANOVA. *P < .05 versus sham within time point, by independent t-test (B), or Bonferroni multiple comparisons procedure (C and G). Summary data are presented as mean ± SE.