Table 1.
Demographic characteristics between cases and controls in children with atopic dermatitis.
| Before matching | After matching | |||||
|---|---|---|---|---|---|---|
| Case group | Control group | P-value* | Case group | Control group | P-value* | |
| (N, %) | (N, %) | (N, %) | (N, %) | |||
| N | 1315 | 6491 | 1251 | 3753 | ||
| Gender (N, %) | ||||||
| Female | 554 (42.1%) | 3357 (51.7%) | < 0.0001 | 523 (41.8%) | 1569 (41.8%) | 1.000 |
| Male | 761 (57.9%) | 3134 (48.3%) | 728 (58.2%) | 2184 (58.2%) | ||
| Age group (N, %) | ||||||
| < 5 | 846 (64.3%) | 3704 (57.1%) | < 0.0001 | 800 (63.9%) | 2400 (63.9%) | 1.000 |
| 5–9 | 436 (33.2%) | 2475 (38.1%) | 421 (33.7%) | 1263 (33.7%) | ||
| > 10 | 33 (2.5%) | 312 (4.8%) | 30 (2.4%) | 90 (2.4%) | ||
| Residential area (N, %) | ||||||
| Taipei area | 538 (40.9%) | 2278 (35.1%) | < 0.0001 | 506 (40.4%) | 1585 (42.2%) | 0.0016 |
| Northern area | 248 (18.9%) | 727 (11.2%) | 239 (19.1%) | 544 (14.5%) | ||
| Central area | 173 (13.2%) | 1046 (16.1%) | 161 (12.9%) | 586 (15.6%) | ||
| Southern area | 196 (14.9%) | 1284 (19.8%) | 190 (15.2%) | 604 (16.1%) | ||
| Kao-Ping area | 147 (11.2%) | 1042 (16.1%) | 144 (11.5%) | 399 (10.6%) | ||
| East area | 13 (1.0%) | 114 (1.8%) | 11 (.9%) | 36 (.9%) | ||
| Comorbidity (N, %) | ||||||
| Allergic rhinitis | 469 (35.7%) | 785 (12.1%) | < 0.0001 | 405 (32.4%) | 1173 (31.3%) | 0.4607 |
| Chronic rhinitis | 159 (12.1%) | 484 (7.5%) | < 0.0001 | 142 (11.4%) | 380 (10.1%) | 0.2194 |
| Acute sinusitis | 811 (61.7%) | 2658 (40.9%) | < 0.0001 | 757 (60.5%) | 2351 (62.6%) | 0.1811 |
| Bronchiolitis | 183 (13.9%) | 287 (4.4%) | < 0.0001 | 139 (11.1%) | 427 (11.4%) | 0.7966 |
*Chi-square test was used to compare patients’ characteristics between case and controls in children with atopic dermatitis and p values < 0.05 indicating statistically significant difference.