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. 2021 Apr 19;12(5):412. doi: 10.1038/s41419-021-03684-x

Fig. 7. miR-186-5p and miR-548c-3p mediated the regulatory effect of circBACH2 on the progression of TNBC in vitro.

Fig. 7

MDA-MB-231 and BT-549 cells were divided into six groups: sh-NC + in-NC, in-NC + sh-circBACH2, sh-NC + in-miR-186-5p, sh-circBACH2 + in-miR-186-5p, sh-NC + in-miR-548c-3p, and sh-circBACH2 + in-miR-548c-3p. A–C Cell proliferation was evaluated using colony formation assay and quantified. D–F Cell migration was evaluated using Transwell assay and quantified. G–I Cell invasion was evaluated using Transwell assay and quantified. *P < 0.05, **P < 0.01, ***P < 0.001 vs sh-NC + in-NC; #P < 0.05, ##P < 0.01, ###P < 0.001 vs in-NC + sh-circBACH2.