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. 2021 Apr 19;7:84. doi: 10.1038/s41420-021-00467-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A QRT-PCR analysis of circSNRK in AAV9 ctrl and AAV9 circSNRK treated rat hearts. ***p < 0.001 vs. AAV9 ctrl group. B Echocardiography analysis was performed at 1day,14days and 28 days after establishment of MI. And quantitative analysis of LVEF and LVFS in the AAV9 circSNRK and AAV9 ctrl groups. ***p < 0.001 vs. Sham + AAV9 ctrl group; ^#p < 0.05, ^##p < 0.01 vs. MI + AAV9 ctrl group. (n = 5–6 for each group). C HE staining images at the border zone 28 days after MI. bar = 25 µm. D Triphenyltetrazolium chloride (TTC) staining of rat ventricular cross-sections at 28 days post-MI, ***P < 0.001 vs. Sham + AAV9 ctrl, ^###P < 0.001 vs. MI + AAV9 ctrl. (n = 5 for each group). E Masson staining images at 28 days after MI and quantitative analyses of infarct size. Red, myocardium; blue, scarred fibrosis. ***p < 0.001 vs. MI + AAV9 ctrl group. ^###P < 0.001 vs. MI + AAV9 ctrl. (n = 5–6 for each group).