Table 6.
ANOVA analysis of central composite design
| Source | SS | DF | MS | F value | p value Prob > F |
|
|---|---|---|---|---|---|---|
| Model | 44.99 | 14 | 3.21 | 61.16 | < 0.0001 | Significant |
| A—Tryptone | 24.80 | 1 | 24.80 | 471.97 | < 0.0001 | |
| B—Meat ex | 1.02 | 1 | 1.02 | 19.35 | 0.0005 | |
| C—Thiamine | 0.33 | 1 | 0.33 | 6.25 | 0.0245 | |
| D—MgSO4 | 0.034 | 1 | 0.034 | 0.65 | 0.4314 | |
| AB | 0.99 | 1 | 0.99 | 18.76 | 0.0006 | |
| AC | 0.63 | 1 | 0.63 | 11.96 | 0.0035 | |
| AD | 0.24 | 1 | 0.24 | 4.50 | 0.0509 | |
| BC | 5.84 | 1 | 5.84 | 111.13 | < 0.0001 | |
| BD | 0.012 | 1 | 0.012 | 0.23 | 0.6393 | |
| CD | 0.30 | 1 | 0.30 | 5.66 | 0.0311 | |
| A2 | 0.53 | 1 | 0.53 | 10.12 | 0.0062 | |
| B2 | 1.55 | 1 | 1.55 | 29.59 | < 0.0001 | |
| C2 | 7.95 | 1 | 7.95 | 151.21 | < 0.0001 | |
| D2 | 2.13 | 1 | 2.13 | 40.51 | < 0.0001 | |
| Residual | 0.79 | 15 | 0.053 | |||
| Lack of fit | 0.78 | 10 | 0.078 | 45.81 | 0.0003 | |
| Pure error | 8.510E−003 | 5 | 1.702E−003 | |||
| Cor total | 45.77 | 29 |
SS Sum of squares, DF Degrees of freedom, MS Mean sum of squares