Table 2.
EPS induced changes in hematological parameters in DMH-treated rats
S. no | Parameter | Normal control (Group I) | Only DMH (Group II) | Standard 5-FU (Group III) | EPS 200 mg/kg b.w (Group IV) | EPS 400 mg/kg b.w (Group V) |
---|---|---|---|---|---|---|
1 | RBC (1012 cells/l) | 4.05 ± 0.58 | 2.10 ± 0.10** | 3.87 ± 0.27 | 3.19 ± 0.25* | 3.46 ± 0.45 |
2 | WBC (cells/10 mm) | 10.60 ± 0.47 | 6.33 ± 0.27** | 10.30 ± 0.38 | 8.66 ± 0.25 | 9.70 ± 0.86 |
3 | Hb (g/100 ml) | 14.57 ± 0.81 | 8.20 ± 0.86** | 12.90 ± 0.53 | 10.80 ± 0.62* | 12.43 ± 0.53 |
4 | Lymphocytes (No/100 WBC) | 85.00 ± 2.36 | 43.33 ± 1.36** | 77.67 ± 2.25 | 60.67 ± 1.86* | 67.00 ± 0.89* |
Hematological parameters where values which were affected by the treatment of DMH (Group II) is brought back to near normal levels by the action of EPS (Group IV and V)
*p < 0.05
**p < 0.01)