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. 2021 Apr 19;11:57. doi: 10.1186/s13568-021-01218-4

Table 3.

Summary of main process data, calculated overall yields and specific growth rates of B. subtilis bioreactor cultivations

Strategy Reference pO2 set-point 20% Fed-batch, constant aeration of 2 L/min Fed-batch, constant aeration
of 1.2 L/min
Fed-batch, constant aeration
of 1.2 L/min
Evaluation until End of batch After batch glucose consumption End of process After batch glucose consumption End of process After batch glucose consumption End of process
B. subtilis strain JABs24 MG1 KM1016 MG14
Time of cultivation (h) 24 22 40 26 46 19 46
CDWmax (g) 77.51 104.55 196.97 61.54 ± 9.21 147.52 ± 8.22 55.78 ± 13.24 150.18 ± 3.33
Surfactinmax (g) 57.43 51.65 104.57 48.47 ± 11.81 82.14 ± 0.91 15.49 ± 6.40 31.56 ± 3.74
YP/X (g/g) 0.741 0.494 0.531 0.776 ± 0.088 0.557 ± 0.024 0.266 ± 0.039 0.211 ± 0.030
YX/S (g/g) 0.145 0.249 0.195 0.161 ± 0.011 0.131 ± 0.005 0.134 ± 0.016 0.123 ± 0.003
YP/S (g/g) 0.108 0.124 0.103 0.127 ± 0.022 0.073 ± 0.001 0.036 ± 0.010 0.026 ± 0.004
q (g/(g∙h)) 0.031 0.022 0.013 0.030 ± 0.003 0.012 ± 0.001 0.014 ± 0.002 0.004 ± 0.001
µ (1/h) 0.222 0.272 0.165 0.204 ± 0.009 0.134 ± 0.005 0.271 ± 0.010 0.128 ± 0.003