Table 2.
The genotype and allele distributions of studied polymorphisms between controls and cases.
| SNPs | Genotype/allele | Controls | Cases | χ2 | P* |
|---|---|---|---|---|---|
| ApoB gene | |||||
| rs1042034 | CC | 373 (57.12%) | 319 (55.48%) | 18.11 | <0.001 |
| CT | 270 (41.35%) | 221 (38.43%) | |||
| TT | 10 (1.53%) | 35 (6.09%) | |||
| T | 290 (22.21%) | 291 (25.30%) | 3.25 | 0.071 | |
| rs679899 | AA | 453 (69.37%) | 409 (71.13%) | 3.27 | 0.195 |
| AG | 188 (28.79%) | 148 (25.74%) | |||
| GG | 12 (1.84%) | 18 (3.13%) | |||
| G | 212 (16.23%) | 172 (15.11%) | 0.57 | 0.448 | |
| rs1367117 | GG | 496 (75.96%) | 434 (75.48%) | 0.04 | 0.981 |
| AG | 147 (22.51%) | 132 (22.96%) | |||
| AA | 10 (1.53%) | 9 (1.57%) | |||
| A | 167 (12.79%) | 150 (13.04%) | 0.04 | 0.850 | |
| rs12720838 | CC | 455 (69.68%) | 393 (68.35%) | 9.70 | 0.008 |
| CT | 192 (29.4%) | 162 (28.17%) | |||
| TT | 6 (0.92%) | 20 (3.48%) | |||
| T | 204 (15.62%) | 202 (17.57%) | 1.68 | 0.195 | |
| PCSK9 gene | |||||
| rs662145 | TT | 505 (77.34%) | 434 (75.48%) | 1.34 | 0.511 |
| CT | 137 (20.98%) | 134 (23.30%) | |||
| CC | 11 (1.68%) | 7 (1.22%) | |||
| C | 159 (12.17%) | 148 (12.87%) | 0.27 | 0.603 | |
| rs45448095 | CC | 544 (83.31%) | 454 (78.96%) | 3.84 | 0.147 |
| CT | 103 (15.77%) | 115 (20.00%) | |||
| TT | 6 (0.92%) | 6 (1.04%) | |||
| T | 115 (8.81%) | 127 (11.04%) | 3.45 | 0.063 |
SNPs, single nucleotide polymorphisms.
*
P was calculated using the χ2-test.